New scientific publication for the APTSol Team. This time the leading journal "European Journal of Pharmaceutical Sciences" with the article entitled "Nanonized itraconazole powders for extemporary oral suspensions: Role of formulation components Studied by a mixture design"
We produced powders containing itraconazole nano-crystals through the combination of High Pressure Homogenization and Spray Drying techniques. These powders have been developed with the intent to use it as a production intermediate for the preparation of extemporary oral suspensions. The role of the various components in getting readily redispersible powder was evaluated through a study of mixtures. The systems obtained showed a greater dissolution performance compared to the untreated product with the techniques adopted, all to the advantage of a better gastro-intestinal absorption of the active ingredient.